The aim of the article is to define the key motives of non-profit organizations for cooperation with companies on socially responsible issues. The case study was conducted in two interrelated parts. Namely, using qualitative interviews with nonprofit organizations operating in the Czech Republic. Subsequently, focus groups were applied for a deeper analysis and evaluation of the attitudes of experts on the issue. The findings suggest that NGOs focus on the needs of local communities which is a key element for possible cooperation with companies that are also seeking to serve these areas. Another key point for collaboration is the desire of both NPOs and companies to address the issues of the community in which the organization is located, to this end companies are willing to sponsor NPOs to help them address these issues. This study fills a gap in the literature on collaboration between the nonprofit and forprofit sectors on socially responsible issues by applying the concept of integrative and community relations in the context of locally owned businesses and community-based nonprofit organizations, which distinguishes this study from the usually studied issue of multinational organizations and their collaboration with the nonprofit sector. The findings from this study offer key points for the leadership of community-based nonprofit organizations interested in establishing relationships with local businesses.